refine.bio
  • Search
      • Normalized Compendia
      • RNA-seq Sample Compendia
  • Docs
  • About
  • My Dataset
github link
Showing
of 24 results
Sort by

Filters

Technology

Platform

accession-icon GSE9412
Transcriptional regulation of aldo-keto reductase 1C1 in human colon cancer cells resistant to methotrexate
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Description

The abstract of the associated publication (Selga E, No V, Ciudad CJ. Biochemical Pharmacology, 2008) is the following:

Publication Title

Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: role in the cell cycle and apoptosis.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE35382
Comparison of gene expression profiles of HT29 cells treated with Instant Caffeinated Coffee or Caffeic Acid versus control.
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

A summary of the work associated to these microarrays is the following:

Publication Title

Coffee polyphenols change the expression of STAT5B and ATF-2 modifying cyclin D1 levels in cancer cells.

Sample Metadata Fields

Cell line, Treatment

View Samples
accession-icon GSE65527
Gene expression after 24h Urolithin A incubation in LNCaP cells
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U219 Array (hgu219)

Description

The identification of new agents that may modulate the progression of cancer cell growth is of great interest. In this regard, dietary agents can be utilized to identify molecular targets to be used as part of a chemopreventive strategy. Walnuts contain several bioactive compounds, including pedunculagin, a polyphenol metabolized by microbiota to form urolithins, namely urolithin A (UA). We performed a genomic analysis to study the effect of UA on androgen-dependent LNCaP prostate adenocarcinoma cells. Cells were incubated with 40M UA for 24 hours, then, RNA was extracted. RNA samples were processed in the automated Biomek FX System (Beckman Coulter), where aRNA was produced, and labeled with Biotin, purified , fragmented and hybridized onto HG U219-24 Array, using the GeneChip HT 3IVT Express Kit . Afterwards, the GeneTitan Multi-Channel (MC) Instrument (Affymetrix) was used to hybridize, wash , stain , and scan the arrays. Microarray results were analyzed using the GeneSpring GX v13.0 software.

Publication Title

Urolithin A causes p21 up-regulation in prostate cancer cells.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE11440
Role of Caveolin 1, E-Cadherin, Enolase 2 and PKCa on resistance to methotrexate in human HT29 colon cancer cells
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

A summary of the work associated to these microarrays is the following:

Publication Title

Role of caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE16648
Networking of differentially expressed genes in human cancer cell lines resistant to methotrexate
  • organism-icon Homo sapiens
  • sample-icon 37 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Networking of differentially expressed genes in human cancer cells resistant to methotrexate.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE16085
Networking of differentially expressed genes in human K562 erythtoblastic leukemia cells resistant to methotrexate
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

A summary of the work associated to these microarrays is the following:

Publication Title

Networking of differentially expressed genes in human cancer cells resistant to methotrexate.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE16070
Networking of differentially expressed genes in human MCF7 breast cancer cells resistant to methotrexate
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

A summary of the work associated to these microarrays is the following:

Publication Title

Networking of differentially expressed genes in human cancer cells resistant to methotrexate.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE16066
Networking of differentially expressed genes in CaCo2 human colon cancer cells resistant to methotrexate
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

A summary of the work associated to these microarrays is the following:

Publication Title

Networking of differentially expressed genes in human cancer cells resistant to methotrexate.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE16082
Networking of differentially expressed genes in human MIA PaCa2 pancreatic cancer cells resistant to methotrexate
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

A summary of the work associated to these microarrays is the following:

Publication Title

Networking of differentially expressed genes in human cancer cells resistant to methotrexate.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE16080
Networking of differentially expressed genes in human MDA-MB-468 breast cancer cells resistant to methotrexate
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

A summary of the work associated to these microarrays is the following:

Publication Title

Networking of differentially expressed genes in human cancer cells resistant to methotrexate.

Sample Metadata Fields

Specimen part, Cell line

View Samples

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

Powered by Alex's Lemonade Stand Foundation

Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

BSD 3-Clause LicensePrivacyTerms of UseContact