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accession-icon GSE13735
Expression data from rice genotypes FL478 and IR29
  • organism-icon Oryza sativa
  • sample-icon 11 Downloadable Samples
  • Technology Badge Icon Affymetrix Rice Genome Array (rice)

Description

Salt Stress response of salt-tolerant genotype FL478 compared to IR29

Publication Title

Comparing genomic expression patterns across plant species reveals highly diverged transcriptional dynamics in response to salt stress.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE6325
Array-based genotyping and expression analysis of barley cv. Maythorpe and Golden Promise
  • organism-icon Hordeum vulgare
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon Affymetrix Barley Genome Array (barley1)

Description

Salt Stress response of salt-tolerant genotype Golden Promise compared to Maythorpe

Publication Title

Array-based genotyping and expression analysis of barley cv. Maythorpe and Golden Promise.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE3170
Barley single feature polymorphisms and drought stress gene expression
  • organism-icon Hordeum vulgare
  • sample-icon 21 Downloadable Samples
  • Technology Badge Icon Affymetrix Barley Genome Array (barley1)

Description

Detection of single feature polymorphisms comparing five barley genotypes. Gene expression under unstressed and drought stressed conditions.

Publication Title

Detecting single-feature polymorphisms using oligonucleotide arrays and robustified projection pursuit.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE46193
Molecular profiles of cognitive aging
  • organism-icon Homo sapiens
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Gene expression was measured from the dentate gyrus and entorhinal cortex harvested from human postmortem samples.

Publication Title

Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48.

Sample Metadata Fields

Age, Specimen part, Subject

View Samples
accession-icon GSE14403
Root-specific transcriptional profiling of contrasting rice genotypes in response to salinity stress
  • organism-icon Oryza sativa indica group
  • sample-icon 23 Downloadable Samples
  • Technology Badge Icon Affymetrix Rice Genome Array (rice)

Description

Analysis of root gene expression of salt-tolerant genotypes FL478, Pokkali and IR63731, and salt-sensitive genotype IR29 under control and salinity-stressed conditions during vegetative growth. Results provide insight into the genetic basis of salt tolerance in indica rice.

Publication Title

Root-specific transcript profiling of contrasting rice genotypes in response to salinity stress.

Sample Metadata Fields

No sample metadata fields

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accession-icon E-MEXP-1220
Transcription profiling by array of human T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
  • organism-icon Homo sapiens
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Description

Study of the gene expression of T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316

Publication Title

Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells.

Sample Metadata Fields

Specimen part, Cell line, Compound

View Samples
accession-icon GSE33391
Cross-species Detection in Barley1 GeneChip Array
  • organism-icon Oryza sativa, Zea mays, Hordeum vulgare, Sorghum bicolor, Triticum aestivum, Avena sativa
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Barley Genome Array (barley1)

Description

This study was conducted to evaluate the efficiency of cross-species detection in Barley1 GeneChip array. We hybridized cRNA derived from first leaves of barley green seedlings (as a control), as well as the same stage of seedling leaf from representative genotypes of wheat, oat, rice, maize, and sorghum. Ten to twenty seedlings for each species were harvested and pooled for RNA preparation, labeling, and hybridization. ****[PLEXdb(http://www.plexdb.org) has submitted this series at GEO on behalf of the original contributor, Rico Caldo. The equivalent experiment is BB1 at PLEXdb.]

Publication Title

A new resource for cereal genomics: 22K barley GeneChip comes of age.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE35480
Analysis of the implication of the DBIRD complex (DBC1 and ZNF326/ZIRD) in gene expression and alternative splicing
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Exon 1.0 ST Array [transcript (gene) version (huex10st)

Description

Alternative mRNA splicing is the main reason vast mammalian proteomic complexity can be achieved with a limited number of genes. Splicing is physically and functionally coupled to transcription and the rate of transcript elongation has a profound effect on splicing. As the nascent pre-mRNA emerges from transcribing RNA polymerase II (RNAPII), it is assembled into a messenger ribonucleoprotein (mRNP) particle that represents its functional form, and the composition of which determines the fate of the mature transcript4. However, factors that connect the transcribing polymerase with the mRNP particle and help integrate transcript elongation with mRNA splicing remain obscure. Here, we characterized the interactome of chromatin-associated mRNP particles and thereby identified Deleted in Breast Cancer 1 (DBC1) and a protein we named ZIRD. These proteins are subunits of a novel protein complex, named DBIRD, which binds directly to RNAPII. DBIRD regulates alternative splicing of a large set of exons embedded in A/T-rich DNA, and is present at the affected exons. RNAi-mediated DBIRD depletion results in region-specific decreases in transcript elongation, particularly across areas encompassing affected exons. These data indicate that DBIRD complex acts at the interface between mRNP particles and RNAPII, integrating transcript elongation with regulation of alternative splicing.

Publication Title

DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.

Sample Metadata Fields

Cell line

View Samples
accession-icon GSE9365
Expression data from barley maturing and germinating grains
  • organism-icon Hordeum vulgare
  • sample-icon 32 Downloadable Samples
  • Technology Badge Icon Affymetrix Barley Genome Array (barley1)

Description

Plant seeds prepare for germination already during seed maturation. We performed a detailed transcriptome analysis of barley grain maturation, desiccation and germination in two tissue fractions (endosperm/aleurone = e/a and embryo = em) using the Affymetrix barley1 chip.

Publication Title

Barley grain maturation and germination: metabolic pathway and regulatory network commonalities and differences highlighted by new MapMan/PageMan profiling tools.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE11200
Expression data from malting barley seeds
  • organism-icon Hordeum vulgare
  • sample-icon 22 Downloadable Samples
  • Technology Badge Icon Affymetrix Barley Genome Array (barley1)

Description

Malting is seed germination under strictly controlled environmental conditions. Malting quality is a complex phenotype that combines a large number of interrelated components, each of which shows complex inheritance. Currently, only a few genes involved in determining malting quality have been characterized. This study combined transcript profiling with phenotypic correlations to identify candidate genes for malting quality.

Publication Title

Differentially expressed genes during malting and correlation with malting quality phenotypes in barley (Hordeum vulgare L.).

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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