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accession-icon GSE118222
Identification of PARPi sensitive transcripts in prostate cancer
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 2.0 ST Array (hugene20st)

Description

Evaluation of the genome wide impact of PARPi gene expression programs

Publication Title

PARP-1 regulates DNA repair factor availability.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE45205
Effects of miR-106a~363 blocking sponge on Sk-ES-1 Ewing Sarcoma Cell line Gene Expression Profile
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.1 ST Array (hugene11st)

Description

The objective of this study was to determine the effects of miR-106a~363 blockade on the gene expression profile of Ewing Sarcoma cell lines (Sk-ES-1 cells)

Publication Title

Growth-promoting role of the miR-106a~363 cluster in Ewing sarcoma.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE43234
Sox7 and Sox17
  • organism-icon Mus musculus
  • sample-icon 11 Downloadable Samples
  • Technology Badge IconIllumina mouseRef-8 v1.1 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.

Sample Metadata Fields

Cell line, Treatment

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accession-icon GSE43233
Gene expression analysis of V5 tagged Sox17 expressing ES cells
  • organism-icon Mus musculus
  • sample-icon 10 Downloadable Samples
  • Technology Badge IconIllumina mouseRef-8 v1.1 expression beadchip

Description

Analysis of the expression of KH2 embryonic stem cells inducibly expressing V5 tagged Sox17 protein. Results provide information on the endodermal gene expression program activated after Sox17 expression in ES cells.

Publication Title

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.

Sample Metadata Fields

Cell line, Treatment

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accession-icon GSE43232
Gene expression analysis of F9 cells double knock-down for Sox7 and Sox17
  • organism-icon Mus musculus
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina mouseRef-8 v1.1 expression beadchip

Description

Analysis of the expression of F9 cells after knockdown of Sox7 and Sox17 during their primitive endoderm differnetiation induction with retinoic acid. Results provide information on the endodermal gene expression program regulated by Sox7 and Sox17.

Publication Title

Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.

Sample Metadata Fields

Cell line, Treatment

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accession-icon GSE51130
Using a rhabdomyosarcoma patient-derived xenograft to examine precision medicine approaches and model acquired resistance
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Original patient tumor is directly implanted in mice xenografts. Tumor is propagated to multiple mice for conduct of 6 arm treatment trials and control. Therapies are selected based on T0 and F0 genomic profiles.

Publication Title

Using a rhabdomyosarcoma patient-derived xenograft to examine precision medicine approaches and model acquired resistance.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE6291
Transcriptome Analysis Multipotent Adult Progenitor Cells (Affy)
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

We compare the transcriptome of two different clones of multipotent adult progenitor cells (MAPCs) using Affymetrix arrays.

Publication Title

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE72406
Identification and targeting of long-term tumor propagating cells in small cell lung cancer
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

FACS sorted TPCs (CD24HighCD44LowEpCAMHigh) and non-TPCs (CD24Low, CD24HighCD44High, and CD24HighCD44LowEpCAMLow) from mouse primary SCLC tumors

Publication Title

Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer.

Sample Metadata Fields

Specimen part

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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