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accession-icon GSE14663
Involvement of the rice LBD37 (OsLBD37) ortholog of Arabidopsis in nitrogen metabolism- and senescence-related processes
  • organism-icon Oryza sativa, Arabidopsis thaliana
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Metabolomic screening applied to rice FOX Arabidopsis lines leads to the identification of a gene-changing nitrogen metabolism.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE14646
Gene expression in aerial parts of rice-Arabidopsis Os-LBD37 FOX plants
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Aerial parts of the rice-Arabidopsis FOX (Full-length cDNA overexpressor) lines K16331 and K19624 harboring the rice FL cDNA of LBD37 (Os-LBD37) were analyzed. LBD37 belongs to the plant- specific LOB- (Lateral Organ Boundary) domain family proteins first characterized in Arabidopsis. Results point towards an involvement of the rice LBD37 ortholog of Arabidopsis in nitrogen metabolism- related processes.

Publication Title

Metabolomic screening applied to rice FOX Arabidopsis lines leads to the identification of a gene-changing nitrogen metabolism.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE14647
Gene expression in leaf blades of the rice Os-LBD37 overexpressor line RK16331-13
  • organism-icon Oryza sativa
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

The 5th and 6th leaf blades of the rice Os-LBD37 overexpressor line RK16331-13 and the empty vector control line FOX3 were examined. LBD37 belongs to the plant- specific LOB- (Lateral Organ Boundary) domain family proteins first characterized in Arabidopsis. Results point towards an involvement of the rice LBD37 (OsLBD37) ortholog of Arabidopsis in nitrogen metabolism- and senescence- related processes.

Publication Title

Metabolomic screening applied to rice FOX Arabidopsis lines leads to the identification of a gene-changing nitrogen metabolism.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE6737
Over-expression of a Type-A Response Regulator Alters Rice Morphology and Cytokinin Metabolism
  • organism-icon Oryza sativa
  • sample-icon 27 Downloadable Samples
  • Technology Badge Icon Affymetrix Rice Genome Array (rice)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Overexpression of a type-A response regulator alters rice morphology and cytokinin metabolism.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE6719
Cytokinin responsive genes in rice
  • organism-icon Oryza sativa
  • sample-icon 23 Downloadable Samples
  • Technology Badge Icon Affymetrix Rice Genome Array (rice)

Description

Cytokinins (CKs) are a class of plant hormones that regulate many aspects of growth and development, including cell division, apical dominance, leaf senescence, nutrient signaling, and shoot differentiation. In the past decade, substantial progress has been made in understanding CK biosynthesis, metabolism and signal transduction. Much of this knowledge is based on research in Arabidopsis, a dicotyledonous model plant. Although cytokinin plays an important role for growth and development in the Gramineae, our knowledge of cytokinin responsive genes in monocotyledonous species is very limited compared to Arabidopsis. The search for genes whose expression is modified by CK has yielded a number of valuable tools that have been used to understand CK signaling and the complex developmental processes under control of this hormone. We tried to identify rice genes regulated by CK using an Affymetrix rice genome array.

Publication Title

Overexpression of a type-A response regulator alters rice morphology and cytokinin metabolism.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE32108
Knockdown effect of CDK8 or CDK19 in HeLa S3 cell
  • organism-icon Homo sapiens
  • sample-icon 15 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Mediator complex has been known as pivotal regulator of RNA polymerase II. Mediator complex has two CDK subunits in vertebrates, named CDK8 and CDK19. To elucidate functional difference between CDK8 and CDK19 in human cell, we employ siRNA mediate knockdown assay using HeLa S3 cell line. According to this assay these CDKs possess highly redundancy in HeLa S3 cell transcription regulation mechanism but in several genes, each CDK shows gene specific regulatory function.

Publication Title

Identification of target genes for the CDK subunits of the Mediator complex.

Sample Metadata Fields

Cell line

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accession-icon GSE6720
Gene expression in OsRR6-overexpression line
  • organism-icon Oryza sativa
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Rice Genome Array (rice)

Description

Cytokinins (CKs) are a class of plant hormones that regulate many aspects of growth and development, including cell division, apical dominance, leaf senescence, nutrient signaling, and shoot differentiation. In the past decade, substantial progress has been made in understanding CK biosynthesis, metabolism and signal transduction. Much of this knowledge is based on research in Arabidopsis, a dicotyledonous model plant. The current model of the CK signaling pathway is a multi-step His-Asp phosphorelay system. Some of the cytokinin-inducible response regulators are thought to act as negative regulators of CK signaling. We tried to identify rice genes regulated by CK-inducible response regulator using an Affymetrix rice genome array and transgenic rice that over-express OsRR6.

Publication Title

Overexpression of a type-A response regulator alters rice morphology and cytokinin metabolism.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE73802
Identification of Drosophila Mid regulated genes in embryos
  • organism-icon Drosophila melanogaster
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

Drosophila midline(mid), encodes a T-box transcription factor that is required for cell fate specification and tissue morphogenesis during a series of developmental processes. However, little is known about the target of Mid.

Publication Title

The T-box transcription factor Midline regulates wing development by repressing wingless and hedgehog in Drosophila.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE37707
Effects of the long noncoding RNA Malat1 on gene expression
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Malat1 is not an essential component of nuclear speckles in mice.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE39979
Expression data from cultured rat astrocytes
  • organism-icon Rattus norvegicus
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Genome 230 2.0 Array (rat2302)

Description

The objective of this study is to search for calcium signal-dependent expression changes.

Publication Title

Calcium-dependent N-cadherin up-regulation mediates reactive astrogliosis and neuroprotection after brain injury.

Sample Metadata Fields

Specimen part

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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