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accession-icon GSE145781
Whole spleen transcriptome during acute phase of infection in a virulent Plasmodium chabaudi chabaudi CB infection
  • organism-icon Mus musculus
  • sample-icon 32 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

Analysis of spleen samples taken throughout the acute phase of infection from mice infected with virulent P. chabaudi CB strain

Publication Title

Transcriptome analysis of blood and spleen in virulent and avirulent mouse malaria infection.

Sample Metadata Fields

Sex, Specimen part, Time

View Samples
accession-icon GSE145634
Rodent malaria parasite RNA does not affect mouse BeadChip results
  • organism-icon Mus musculus, Plasmodium chabaudi
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

Rodent malaria parasite RNA hybridized on Illumina Mouse WG-6 v2.0 Expression BeadChip

Publication Title

Transcriptome analysis of blood and spleen in virulent and avirulent mouse malaria infection.

Sample Metadata Fields

Sex, Specimen part

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accession-icon GSE25557
Characterization of Definitive Endoderm formation from HESC and iPSC lines by Microarray analysis
  • organism-icon Homo sapiens
  • sample-icon 23 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

HESC-H9 and iPSC lines 3.5, 3.6 and 3.12 were analyzed using Affymetrix microarray before and after Definitive Endoderm (DE) formation. DE was induced using the ActivinA differentiation protocol described by D'Amour et al., 2006 (PMID: 16258519) Clustering analysis of transcripts that were differentially regulated during DE formation indicated that iPSC lines 3.5 and 3.12 differentiate in manner that is highly similar to HESC-H9 cells iPSC line 3.6 had a more divergent transcriptional profile.

Publication Title

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE39067
Stability of miRNA in FFPE tumour samples exhibiting degraded mRNA
  • organism-icon Homo sapiens
  • sample-icon 336 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Exon 1.0 ST Array [probe set (exon) version (huex10st)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE146911
Antitumor Activity of Z-endoxifen in Aromatase Inhibitor-Sensitive and Resistant Estrogen Receptor-Positive Breast Cancer
  • organism-icon Homo sapiens
  • sample-icon 11 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

The overarching goal of this study was to explore the antitumor activity of Z-endoxifen, a tamoxifen metabolite, with first-line endocrine therapies tamoxifen and letrozole in the letrozole-sensitive MCF7 aromatase expressing model (MCF7AC1), and with second-line endocrine therapies including tamoxifen, fulvestrant, exemestane, and exemestane plus everolimus, in letrozole-resistant MCF7 model (MCF7LR) in vivo.

Publication Title

Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer.

Sample Metadata Fields

Cell line, Treatment

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accession-icon SRP001417
modENCODE RNA-Seq of Drosophila Kc167
  • organism-icon Drosophila melanogaster
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer

Description

Deep Sequencing of Kc167 mRNA. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf Overall design: Seq of Poly-A+ RNA from D. melanogaster Kc167

Publication Title

The transcriptional diversity of 25 Drosophila cell lines.

Sample Metadata Fields

Cell line, Subject

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accession-icon GSE89997
Expression data from 2 cohorts of human pancreatic ductal adenocarcinoma (PDAC) tumors
  • organism-icon Homo sapiens
  • sample-icon 30 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Transcriptome Array 2.0 (hta20)

Description

In this dataset, we included expression data obtained from 30 resected human PDAC tumors, to examine what genes are differentially expressed in different cohorts that might lead to various outcomes

Publication Title

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE63941
Expression data from cultured human esophageal squamous cell carcinoma cell lines and cultured human fibroblasts.
  • organism-icon Homo sapiens
  • sample-icon 26 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Cancer cells express different sets of receptor type tyrosine kinases. These receptor kinases may be activated through autocrine or paracrine mechanisms. Fibroblasts may modify the biologic properties of surrounding cancer cells through paracrine mechansms.

Publication Title

The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE62947
Expression Data from DMSO or SRPIN803 treated ARPE-19 cells
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

We used microarrays to evaluate the effect of SRPIN803 on gene expression in ARPE-19 cells.

Publication Title

Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice.

Sample Metadata Fields

Cell line

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accession-icon GSE32614
Effects of Aging and Anatomic Location on Gene Expression in Human Retina
  • organism-icon Homo sapiens
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Objective: To determine the effects of age and topographic location on gene expression in human neural retina.

Publication Title

Effects of aging and anatomic location on gene expression in human retina.

Sample Metadata Fields

Sex, Age

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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