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accession-icon GSE18942
TAP-ORC2 and control ChIP experiments in Drosophila Kc167 cells
  • organism-icon Drosophila melanogaster
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome 2.0 Array (drosophila2)

Description

Expression data from Kc167 cells under normal conditions. Used to assess expression levels of genes with ORC bound at promoter.

Publication Title

Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading.

Sample Metadata Fields

Cell line

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accession-icon GSE10230
Analysis of RNA distribution between pseudopodia and cell bodies in response to LPA stimulation or fibronectin
  • organism-icon Mus musculus
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE10227
Analysis of RNA distribution between pseudopodia and cell bodies in response to Fibronectin
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

The goal of the study was to identify on a genome-wide scale RNAs that are enriched at the leading edge of migrating cells. For this, we employed a fractionation method in which cells are plated on a microporous filter whose bottom side only is coated with fibronectin. The cells thus polarize and extend pseudopodial protrusions towards the bottom surface. These protruding pseudopodia can then be physically isolated from the bottom surface of the filter and their contents compared with the remaining cell bodies, which are isolated from the upper surface of the filter.

Publication Title

Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE10226
Analysis of RNA distribution between pseudopodia and cell bodies in response to LPA stimulation
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

The goal of the study was to identify on a genome-wide scale RNAs that are enriched at the leading edge of migrating cells. For this, we employed a fractionation method in which serum-starved cells are first plated and allowed to spread on a microporous filter. Addition of LPA at the bottom side of the filter induces the cells to polarize and extend pseudopodial protrusions. These protruding pseudopodia can then be physically isolated from the bottom surface of the filter and their contents compared with the remaining cell bodies, which are isolated from the upper surface of the filter.

Publication Title

Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE49129
Otitis Media Impact on Ear
  • organism-icon Mus musculus
  • sample-icon 31 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Otitis media impacts hundreds of mouse middle and inner ear genes.

Sample Metadata Fields

Age, Specimen part, Treatment

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accession-icon GSE49128
Otitis Media Impact on Middle Ear
  • organism-icon Mus musculus
  • sample-icon 17 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Objective: Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken. Ninety-nine percent of mouse genes are shared in the human, so these studies are relevant to the human condition.

Publication Title

Otitis media impacts hundreds of mouse middle and inner ear genes.

Sample Metadata Fields

Age, Specimen part, Treatment

View Samples
accession-icon GSE49122
Otitis Media Impact on Inner Ear
  • organism-icon Mus musculus
  • sample-icon 14 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Objective: Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken. Ninety-nine percent of mouse genes are shared in the human, so these studies are relevant to the human condition.

Publication Title

Otitis media impacts hundreds of mouse middle and inner ear genes.

Sample Metadata Fields

Age, Specimen part, Treatment

View Samples
accession-icon GSE17784
Gene expression in FACS-purified cortical projection neurons
  • organism-icon Mus musculus
  • sample-icon 38 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302), Affymetrix Mouse Expression 430A Array (moe430a)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons.

Sample Metadata Fields

Specimen part

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accession-icon GSE47495
Transcriptional profiling of left ventricle and peripheral blood cells in rats with post-myocardial infarction
  • organism-icon Rattus norvegicus
  • sample-icon 34 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Gene 1.0 ST Array (ragene10st)

Description

Myocardial infarction (MI) often results in left ventricular (LV) remodeling followed by heart failure (HF). It is of great clinical importance to understand the molecular mechanisms that trigger transition from compensated LV injury to HF and to identify relevant diagnostic biomarkers. In this study, we performed transcriptional profiling of LVs in rats with a wide range of experimentally induced infarct sizes and of peripheral blood mononuclear cells (PBMCs) in animals that developed HF.

Publication Title

Transcriptional profiling of left ventricle and peripheral blood mononuclear cells in a rat model of postinfarction heart failure.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE17783
Analysis of gene expression in FACS-purified cortical projection neurons using Affymetrix 430 2.0 microarrays
  • organism-icon Mus musculus
  • sample-icon 19 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Expression 430A Array (moe430a), Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

3 subtypes of cortical projection neurons were purified by fluorescence-activated cell sorting (FACS) at 4 different stages of development from mouse cortex. A detailed description of the data set is described in Arlotta, P et al (2005) and Molyneaux, BJ et al (2009). The hybridization cocktails used here were originally applied to the Affymetrix mouse 430A arrays and submitted as GEO accession number GSE2039. The same hybridization cocktails were then applied to the Affymetrix mouse 430 2.0 arrays, and those data are contained in this series.

Publication Title

Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons.

Sample Metadata Fields

Specimen part

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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