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accession-icon GSE25484
Fetal programming of hepatic transcriptome in response to gestational dietary protein levels in the pig
  • organism-icon Sus scrofa
  • sample-icon 121 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

A high protein diet during pregnancy affects hepatic gene expression of energy sensing pathways along ontogenesis in a porcine model.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE33740
Fetal programming of muscle transcriptome in response to gestational dietary protein levels in the pig
  • organism-icon Sus scrofa
  • sample-icon 67 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE25483
Fetal programming of hepatic transcriptome in response to gestational dietary protein levels in the pig (HP data set)
  • organism-icon Sus scrofa
  • sample-icon 62 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

German landrace gilts were fed a high protein diet (HP, 30% CP) throughout their whole pregnancy. Subsequently hepatic transcriptome profiles of the offspring were analysed at prenatal (94 dpc) and postnatal stages (1, 28, 188 dpn)

Publication Title

A high protein diet during pregnancy affects hepatic gene expression of energy sensing pathways along ontogenesis in a porcine model.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE25482
Fetal programming of hepatic transcriptome in response to gestational dietary protein levels in the pig (AP data set)
  • organism-icon Sus scrofa
  • sample-icon 59 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

German landrace gilts were fed an adequate protein diet (AP, 12% CP) throughout their whole pregnancy. Subsequently hepatic transcriptome profiles of the offspring were analysed at prenatal (94 dpc) and postnatal stages (1, 28, 188 dpn).

Publication Title

A high protein diet during pregnancy affects hepatic gene expression of energy sensing pathways along ontogenesis in a porcine model.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE33738
Fetal programming of muscle transcriptome in response to gestational dietary protein levels in the pig [HP]
  • organism-icon Sus scrofa
  • sample-icon 24 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

German landrace gilts were fed a high protein diet (HP, 30% CP) throughout their whole pregnancy. Subsequently muscle transcriptome profiles of the offspring were analysed at prenatal (94 dpc) and postnatal stages (1, 28, 188 dpn)

Publication Title

Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE33739
Fetal programming of muscle transcriptome in response to gestational dietary protein levels in the pig [LP]
  • organism-icon Sus scrofa
  • sample-icon 23 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

German landrace gilts were fed a low protein diet (LP, 6% CP) throughout their whole pregnancy. Subsequently muscle transcriptome profiles of the offspring were analysed at prenatal (94 dpc) and postnatal stages (1, 28, 188 dpn)

Publication Title

Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE33737
Fetal programming of muscle transcriptome in response to gestational dietary protein levels in the pig [AP]
  • organism-icon Sus scrofa
  • sample-icon 20 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

German landrace gilts were fed an adequate protein diet (AP, 12% CP) throughout their whole pregnancy. Subsequently muscle transcriptome profiles of the offspring were analysed at prenatal (94 dpc) and postnatal stages (1, 28, 188 dpn)

Publication Title

Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways.

Sample Metadata Fields

Specimen part

View Samples
accession-icon SRP118847
Comparison of RNA expression of conditional Nmi knockout mammary epithelial cells to the wildtype control
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

The goal of this study was to compare mRNA from mammary epithelial cells of 3 mammary-specific Nmi knockout FVB with corresponding wildtype control. This was performed to obtain clues to the signaling pathways that were impacted in the mammary epithelial cells upon knocking-out Nmi expression. Overall design: To determine how the loss of Nmi contributed to a hyper-proliferative phenotype during puberty and lactation, we performed global RNAseq analysis from enriched mammary epithelial organoids from lactation day1 (L1), the time when Nmi protein expression in normal mammary epithelium is at its highest level. We compared 2 groups with 3 mice/group. We used second and third mammary glands of each mouse. These glands were isolated from mice on the first day of lactation, minced and dissociated in digestion medium (HBSS containing collagenase I (Sigma Aldrich, St. Louis, MO) (1mg/mL) and Pronase (Sigma Aldrich) (0.1mg/mL)) for two hours at 37C with shaking. Epithelial organoids were washed in PBS and enriched by pulse centrifugation to 1500rpm at least three times before subsequent assays.

Publication Title

Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors.

Sample Metadata Fields

Specimen part, Subject

View Samples
accession-icon GSE7553
Gene Expression Patterns Involved in the Malignant Transformation and Progression of Metastatic Melanoma
  • organism-icon Homo sapiens
  • sample-icon 86 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Metastatic melanoma is a deadly disease while non-metastatic melanoma and other cutaneous tumor types are usually cured with surgical removal of the primary tumors. This study evaluated gene expresion to determine if gene expression differences existed which would allow one to identify the metastatic tumors based on the expression of specific genes.

Publication Title

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE28133
Transcriptomic analysis of human retinal detachment (RD) reveals both inflammation and photoreceptor death
  • organism-icon Homo sapiens
  • sample-icon 31 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

We have used surgical specimens to perform a differential analysis of the transcriptome of human retinal tissues following detachment.

Publication Title

Transcriptomic analysis of human retinal detachment reveals both inflammatory response and photoreceptor death.

Sample Metadata Fields

Subject

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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