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accession-icon GSE140179
Effect of SPINK1 and IL-6 knockdown in JHOC9 and JHOC5 ovarian clear cell carcinoma cells
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Transcriptome Array 2.0 (hta20)

Description

Response of JHCO9 and JHOC5 cells to infection with NT (control) lentivirus or one of two knockdown lentiviruses, SPINK1 KD or IL-6 KD.

Publication Title

Targeting an autocrine IL-6-SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE50931
MMP3 treatment of Panc-2 cells
  • organism-icon Homo sapiens
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Response of pancreas cancer cells to treatment with recombinant MMP3

Publication Title

Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma.

Sample Metadata Fields

Specimen part, Cell line, Treatment

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accession-icon GSE56909
MMP3 treatment of SCp2 mouse mammary epithelial cells
  • organism-icon Mus musculus
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Response of mouse mammary epithelial cells to treatment with MMP3

Publication Title

ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail.

Sample Metadata Fields

Specimen part, Treatment

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accession-icon GSE63354
Regulation of Epithelial-Mesenchymal Transition in Breast Cancer Cells by Cell Contact and Adhesion
  • organism-icon Mus musculus, Homo sapiens
  • sample-icon 19 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2), Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE63331
Density variation and MMP3 treatment of SCp2 mouse mammary epithelial cells
  • organism-icon Mus musculus
  • sample-icon 14 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Response of mouse mammary epithelial cells to different cell densities and treatment with MMP3

Publication Title

Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.

Sample Metadata Fields

Specimen part, Cell line

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accession-icon GSE63353
Density variation of MCF10A human breast epithelial cells
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Response of mammary epithelial cells to different cell densities

Publication Title

Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.

Sample Metadata Fields

Specimen part, Cell line

View Samples
accession-icon GSE13496
Aging hematopoietic progenitor/stem cells
  • organism-icon Homo sapiens
  • sample-icon 29 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

To determine how aging impacts gene expression in hematopoietic stem cells (HSCs), human CD34+ cells from bone marrow (34BM) and mobilized stem cell products (34P38NPBSC) were examined using microarray-based expression profiling. Differential expression changes were confirmed by microarray comparisons of younger and older expanded T-cell populations.

Publication Title

Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE29522
Expression data from human CD34+ HPC subpopulations isolated from umbilical cord blood (Haddad et al. Blood 104:3918, 2004)
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

We used microarrays to analyze the gene expression profile of CD34+CD45RA+CD7+, CD34+CD45RA+CD10+CD19- and CD34+CD45+CD7-CD10-CD19- HPCs isolated from umbilical cord blood

Publication Title

Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood.

Sample Metadata Fields

Specimen part

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accession-icon GSE1159
Expression profiles of acute myeloid leukemia patient samples
  • organism-icon Homo sapiens
  • sample-icon 291 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Expression profiles of acute myeloid leukemia patient samples.

Publication Title

Identification of genes with abnormal expression changes in acute myeloid leukemia.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE9476
Abnormal Expression Changes in AML
  • organism-icon Homo sapiens
  • sample-icon 64 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Acute myeloid leukemia (AML) is one of the most common and deadly forms of hematopoietic malignancies. We hypothesized that microarray studies could identify previously unrecognized expression changes that only occur only in AML blasts. We were particularly interested in those genes with increased expression in AML, believing that these genes may be potential therapeutic targets.

Publication Title

Identification of genes with abnormal expression changes in acute myeloid leukemia.

Sample Metadata Fields

Sex, Disease

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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