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accession-icon GSE46706
Expression data generated from post-mortem human brain tissue originating from neurologically and neuropathologically control individuals
  • organism-icon Homo sapiens
  • sample-icon 2462 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Exon 1.0 ST Array [transcript (gene) version (huex10st)

Description

This data set was generated by the UK Brain Expression Consortium and consists of gene expression data generated from post-mortem human brain samples, dissected from 10 brain regions and originating from a large cohort of neurologically and neuropathologically normal individuals.

Publication Title

Analysis of gene expression data using a linear mixed model/finite mixture model approach: application to regional differences in the human brain.

Sample Metadata Fields

Sex, Disease, Subject

View Samples
accession-icon GSE60862
Gene-level analysis of 1231 samples originating from 134 Caucasian individuals
  • organism-icon Homo sapiens
  • sample-icon 1231 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Exon 1.0 ST Array [transcript (gene) version (huex10st)

Description

This data set was generated by the UK Brain Expression Consortium and consists of gene expression data generated from post-mortem human brain samples, dissected from 10 brain regions and originating from a large cohort of neurologically and neuropathologically normal individuals.

Publication Title

Widespread sex differences in gene expression and splicing in the adult human brain.

Sample Metadata Fields

Sex, Disease, Subject

View Samples
accession-icon GSE60863
Exon-level analysis of 1231 samples originating from 134 Caucasian individuals
  • organism-icon Homo sapiens
  • sample-icon 1231 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Exon 1.0 ST Array [transcript (gene) version (huex10st)

Description

This data set was generated by the UK Brain Expression Consortium and consists of gene expression data generated from post-mortem human brain samples, dissected from 10 brain regions and originating from a large cohort of neurologically and neuropathologically normal individuals.

Publication Title

Widespread sex differences in gene expression and splicing in the adult human brain.

Sample Metadata Fields

Sex, Disease, Subject

View Samples
accession-icon GSE20186
Systematic meta-analysis and replication of genome-wide expression studies of Parkinson's disease
  • organism-icon Homo sapiens
  • sample-icon 36 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a), Illumina HumanHT-12 V3.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease.

Sample Metadata Fields

Sex, Age, Specimen part, Disease

View Samples
accession-icon GSE20146
Expression analysis of dissected GPi in Parkinson's disease
  • organism-icon Homo sapiens
  • sample-icon 20 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Genome-wide transcriptome analysis of expression changes in Globus Pallidus interna (GPi) from Parkinson's disease brain tissue versus control brain tissue.

Publication Title

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease.

Sample Metadata Fields

Sex, Specimen part, Disease, Disease stage

View Samples
accession-icon GSE20141
Expression analysis of laser-dissected SNpc neurons in Parkinson's disease
  • organism-icon Homo sapiens
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Genome-wide transcriptome analysis of expression changes in laser-dissected SNpc neurons from Parkinson's disease brain tissue versus control brain tissue.

Publication Title

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease.

Sample Metadata Fields

Specimen part, Disease, Disease stage

View Samples
accession-icon GSE20163
Systematic meta-analysis and replication of genome-wide expression studies of Parkinson's disease: 2
  • organism-icon Homo sapiens
  • sample-icon 17 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Systematic meta-analysis and replication of genome-wide expression studies identifies molecular pathways of Parkinson's disease.

Publication Title

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease.

Sample Metadata Fields

Age, Specimen part, Disease

View Samples
accession-icon GSE20153
Expression analysis of lymphoblast cells lines in Parkinson's disease
  • organism-icon Homo sapiens
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Genome-wide transcriptome analysis of expression changes in EBV transformed cell lines from the Coriell Cell Repository in Parkinson and Control subjects.

Publication Title

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease.

Sample Metadata Fields

Sex, Disease, Disease stage

View Samples
accession-icon GSE20164
Systematic meta-analysis and replication of genome-wide expression studies of Parkinson's disease: 3
  • organism-icon Homo sapiens
  • sample-icon 11 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Systematic meta-analysis and replication of genome-wide expression studies identifies molecular pathways of Parkinson's disease.

Publication Title

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease.

Sample Metadata Fields

Sex, Age, Specimen part, Disease

View Samples
accession-icon GSE20314
Systematic meta-analysis and replication of genome-wide expression studies of Parkinsons disease: 4
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Analysis of substantia nigra from postmortem brains of 4 patients with Parkinsons disease (PD). Results provide insight into the molecular processes perturbed in the PD substantia nigra.

Publication Title

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease.

Sample Metadata Fields

Sex, Age, Specimen part, Disease

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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