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SRP065920
Mus musculus
185 Downloadable Samples
Illumina HiSeq 2500
Description
To test the "one-neuron-one-receptor" rule of olfactory receptor expression, we sequenced the transcriptomes of single olfactory sensory neurons from the main olfactory epithelium of adult (1 to 3 months) and newborn mice (postnatal day 4 to 10).
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Homo sapiens
- 18 Downloadable Samples
- Illumina HiSeq 2000
Description
We report the biological activity of a Py-Im polyamide targeted to the sequence 5'-WGWWCW-3', which is found in a subset of ARE half-sites. This molecule reduces the growth of enzalutamide-resistant LREX' cells, both in vitro and in vivo. Gene expression changes associated with polyamide treatment in both settings are deposited here.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Homo sapiens
- 4 Downloadable Samples
- Illumina HiSeq 2000
Description
VCaP cells were treated with 10uM of a Py-Im polyamided targeted to the DNA sequence 5''-WGWWCW-3'' for 24hrs. Gene expression changes are normalized to untreated VCaP cells.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Age, Specimen part, Cell line
View Samples- Homo sapiens
- 48 Downloadable Samples
- Illumina HiSeq 2500
Description
Gene expression for shNT, shTRRAP-a, and shTRRAP-b expressing cells at ALI day 4 and day 14 was measured using RNA sequencing technology. Each experimental condition was performed in duplicate with two independent donors. Cells expressing the shRNA constructs (RFP+) were sorted by FACS, and the RNA was isolated and prepared for next generation sequencing analysis.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Disease, Treatment
View Samples- Mus musculus
- 24 Downloadable Samples
- Illumina HiSeq 2500
Description
We performed unbiased high-throughput RNA sequencing (mRNA-seq) of total RNA samples isolated from Tsc1-deficient livers in Cre- or Cre+ mice.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Disease, Cell line, Treatment
View Samples- Mus musculus
- 8 Downloadable Samples
- Illumina HiSeq 2500
Description
To study gene expression in liver regeneration, we subjected control mice to DDC (1,4-dihydro-2,4,6-trimethyl-pyridine-3,5-dicarboxylate ) diet for 16 days, isolated EpCam+ CD31-/CD45-/Ter119- cells using fluorescence-activated cell sorting and used these cells for single cell transcriptome analysis.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line, Treatment
View Samples- Danio rerio
- 7 Downloadable Samples
Affymetrix Zebrafish Genome Array (zebrafish)
Description
Effect of ethanol or nicotine exposure on gene expression compared to control. Duplicate arrays from ethanol or nicotine treated animals compared with triplicate arrays from paired control animals. In total 4 treatment arrays (2 ethanol, 2 nicotine) and 3 control arrays (from control animals treated in parallel with ethanol-treated fish and nicotine-treated fish.)
Publication Title
Gene expression changes in a zebrafish model of drug dependency suggest conservation of neuro-adaptation pathways.
Sample Metadata Fields
Specimen part, Compound
View Samples- Drosophila melanogaster
- 27 Downloadable Samples
- Illumina HiSeq 2500
Description
No description.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line, Treatment
View Samples- Homo sapiens
- 16 Downloadable Samples
- Affymetrix Human Genome U133A 2.0 Array (hgu133a2)
Description
Study of the gene expression of T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
Publication Title
Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells.
Sample Metadata Fields
Specimen part, Cell line, Compound
View Samples- Homo sapiens
- 6 Downloadable Samples
- Illumina HiSeq 4000
Description
We propose a microfluidic strategy to generate abundant brain organoids and further explore neurogenesis in fetal brain exposed to ethanol.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Disease, Cell line, Treatment
View Samples