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accession-icon E-MEXP-1234
Transcription profiling of mouse periglomerular cells from laser microdissection (LMD) samples
  • organism-icon Mus musculus
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Analysis of expression of periglomerular cells from laser microdissection (LMD) samples

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples
accession-icon SRP074687
Mus musculus Transcriptome or Gene expression
  • organism-icon Mus musculus
  • sample-icon 5 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

To transcriptionally profile necklace olfactory sensory neurons.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon SRP175144
RNA sequencing of Drosophila eyes expressing nuclear SREBP
  • organism-icon Drosophila melanogaster
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

No description.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Cell line

View Samples
accession-icon SRP117696
RNA-seq timecourse analysis during zebrafish heart looping morphogenesis
  • organism-icon Danio rerio
  • sample-icon 24 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2000

Description

During embryogenesis the heart forms as a linear tube that then undergoes multiple simultaneous morphogenetic events to obtain its mature shape. To understand the gene regulatory networks (GRNs) driving this phase of heart development, during which many congenital heart disease malformations likely arise, we conducted an RNA-seq timecourse in zebrafish from 30 hpf to 72 hpf and identified 5861 genes with altered expression. We clustered the genes by temporal expression pattern, identified transcription factor binding motifs enriched in each cluster, and generated a model GRN for the major gene batteries in heart morphogenesis.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP159685
Mus musculus Raw sequence reads
  • organism-icon Mus musculus
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

This project aims to identify genes that are differentially expressed by premyelinating oligodendrocytes in the absence of transcription factor EB (TFEB). Premyelinating oligodendrocytes were acutely purified by immunopanning approach from P12 Olig2-Cre; TFEB F/+ or P12 Olig2-Cre; TFEB F/F mouse brains. Bulk sequencing were performed with 4 biological replicates per genotype.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

View Samples
accession-icon GSE80061
Genome-wide expression data from hippocampus of control and Noonan syndrom (Ptpn11D61Y) mice in response to neuronal stimulation
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 2.0 ST Array (mogene20st)

Description

Microarrays were used to identify the differentially expressed genes in the hippocampus of control and Noonan syndrom mice at basal state and in response to 4AP-Bic stimulation (10 min). Functional analysis was performed to determine the biological significance of the data.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE4623
gene expression profiling of NFIA deficient mice brain
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Murine Genome U74A Version 2 Array (mgu74av2)

Description

Background. Nuclear factor I-A (NFI-A), a phylogenetically conserved transcription/replication protein, plays a crucial role in mouse brain development. Previous studies showed that disruption of the Nfia gene in mice leads to perinatal lethality, corpus callosum agenesis, and hydrocephalus.

Publication Title

Gene expression analysis of nuclear factor I-A deficient mice indicates delayed brain maturation.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE9254
Normal human colorectal mucosa, cecum, ascending, transverse, sigmoid and rectum
  • organism-icon Homo sapiens
  • sample-icon 17 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Normal human colorectal mucosa was sampled at points along the colon.

Publication Title

Map of differential transcript expression in the normal human large intestine.

Sample Metadata Fields

Specimen part

View Samples
accession-icon SRP056985
Homo sapiens Raw sequence reads
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2000

Description

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Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon E-MEXP-380
Transcription profiling of human NK cells sorted into CD56dim and CD56bright NK cell subpopulations
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133B Array (hgu133b), Affymetrix Human Genome U133A Array (hgu133a)

Description

Human NK cells were sorted into CD56dim and CD56bright NK cell subpopulations. In order to define characteristics of both populations gene profiling was performed using Affymetrix arrays U133a and U133B.

Publication Title

Gene and protein characteristics reflect functional diversity of CD56dim and CD56bright NK cells.

Sample Metadata Fields

Specimen part

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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