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accession-icon E-MTAB-2220
mouse hepatic gene whole transcript expression
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 2.0 ST Array (mogene20st)

Description

Whole transcript expression analysis was performed on liver biopsy from wild mice,DEN model mice and cell-treated mice(2 mice per group)

Publication Title

Transplantation of periportal vessel stem cells promotes liver injury repair in cirrhotic mice

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE53092
Searching for target genes of miR-429 in HCCLM3 cells
  • organism-icon Homo sapiens
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

miRNAs are an class of small noncoding RNAs and about 21-25 nucleotides in length. miRNAs inhibit the translation or induce mRNA degradation by binding to the 3 UTR of target mRNAs and have been identified as the tumor promoters or suppressors regulating the progression of cancers. miR-429, which is a member of an evolutionarily conserved family of miRNAs that includes miR-200b, miR-200a, miR-200c and miR-141, is expressed in various epithelial tissues. Our goal is to search the possible target genes of miR-429 in human liver cancer cell line HCCLM3.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Cell line, Treatment

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accession-icon GSE38080
Hsp27 acts as a master molecular chaperones and plays an essential role in hepatocellular carcinoma metastasis
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Hsp27 can regulate multiply signaling pathway and protect HCC cells apoptosis by mediating interaction with its cochaperones

Publication Title

No associated publication

Sample Metadata Fields

Cell line

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accession-icon SRP070915
Homo sapiens Transcriptome or Gene expression
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2500

Description

we characterized the small RNA content of exosomes derived from gastric cancer cell lines by deep sequencing

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP061670
Homo sapiens Raw sequence reads
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2500

Description

We differentiated hESC into retinal pigment epithelial cells using two methods (three-dimensional culture and spontaneous differentiation methods). We investigated which kind of RPE cells derived from hESC showed similar gene expression patterns to those of human fetal native RPE.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP078083
Single cell RNA-seq analysis of a squamous cell carcinoma of urinary bladder
  • organism-icon Homo sapiens
  • sample-icon 95 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

We use single cell RNA-seq method to analysis the transcriptional heterogeneity in squamous cell carcinoma of urinary bladder. The single cell sequencing approach is based on the method of single-cell tagged reverse transcription (STRT).

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part

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accession-icon SRP101761
RNA-seq identifies ß-estradiol treatment in U2OS osteosarcoma cell
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

This study was to identify gene expression profile change associated withß-estradiol treatment in osteosarcoma cells by high-throughput RNA sequencing

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon SRP095590
RNA-sequencing celecoxib-treated lung squamous cell carcinoma cell line
  • organism-icon Homo sapiens
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

Celecoxib is an inhibitor of cyclooxygenase-2-incuced lung squamous cell carcinoma (LSQCC). The study aims to provide novel insight into celecoxib’s chemoprevention

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

View Samples
accession-icon GSE25436
Expression data from melanoma cell lines
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Differential gene expression analysis of parental and sub-lines of melanoma cell line resistant to F5 CTL lymphocyte

Publication Title

Molecular mechanism of MART-1+/A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction.

Sample Metadata Fields

Cell line

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accession-icon GSE22487
Expression data from neonatal pig skeletal muscle
  • organism-icon Sus scrofa
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

Muscle development and growth is an economically important process in the pig.The neonatal period is another important stage for the pig when the most rapid gain occurring in skeletal muscle.Gene expresseion changes during fetal and postnatal skeletal muscle development that can be used to enhance pig production efficiency, as well as for comparative developmental biology using the pig as a model for other mammalian species.

Publication Title

Gene expression profiling of skeletal muscle of nursing piglets.

Sample Metadata Fields

Specimen part

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...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

Powered by Alex's Lemonade Stand Foundation

Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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