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accession-icon SRP069080
Zea mays Transcriptome or Gene expression
  • organism-icon Zea mays
  • sample-icon 42 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

This study was designed to identify root specific transcriptome variation that occurs across genotypically diverse maize lines.

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part, Disease

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accession-icon SRP187352
Glycine max Transcriptome
  • organism-icon Glycine max
  • sample-icon 15 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

Transcriptome profiling is performed to reveal how Brassinosteroids (BRs) play a crucial role for plant vegetative growth and reproductive development.

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part

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accession-icon E-MEXP-209
Transcription profiling of wounds from ovariectomized MIF null mice and controls to investigate the role of MIF during wound healing using BALB/C MIF null mice
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Expression 430A Array (moe430a)

Description

The aim of this experiment was to investigate the role of MIF during wound healing using BALB/C MIF null mice and in the context of reduced estrogen-associated impaired healing using ovariectomized mice (a mouse model of age-associated delayed healing). Ageing is associated with delayed cutaneous wound healing resulting from reduced estrogen levels. Macrophage migration inhibitory factor (MIF - NCBI RefSeq: NM_010798) is thought to mediate the effects of estrogen on wound healing. Gene expression was compared between wounds from ovariectomized MIF null mice and controls.

Publication Title

Macrophage migration inhibitory factor: a central regulator of wound healing.

Sample Metadata Fields

Sex, Age, Specimen part, Subject

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accession-icon SRP076153
Glycine max strain:Williams 82 Raw sequence reads
  • organism-icon Glycine max
  • sample-icon 9 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer

Description

Identification and comparative analysis of differential gene expression in soybean leaf tissue under drought and flooding stress revealed by RNA-Seq

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part

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accession-icon E-MEXP-1232
Transcription profiling by array of skin wound samples from rats treated with the 5alpha-reductase inhibitor MK-434
  • organism-icon Rattus norvegicus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Expression 230A Array (rae230a)

Description

The present study aimed to delineate the central mechanisms by which androgens delay wound repair. Blocking the conversion of testosterone to 5alpha-dihydrotestosterone (DHT) by 5alpha-reductase limits its ability to impair skin wound healing, suggesting that DHT is a more potent inhibitor of repair than is testosterone. This study aims to identify, through transcription profiling, potential mechanisms by which the 5alpha-reductase inhibitor MK-434 modulates repair. Microarray analysis of wound RNA samples from rats in which the transformation of testosterone to DHT is prevented has identified biological processes and key individual genes through which DHT may contribute to the altered healing profile in such animals. These include genes with putative roles in wound contraction and re-epithelialization.

Publication Title

5alpha-dihydrotestosterone (DHT) retards wound closure by inhibiting re-epithelialization.

Sample Metadata Fields

Sex, Age, Specimen part, Compound

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accession-icon E-MEXP-1074
Transcription profiling by array of excisional biopsy wounds from young and old human subjects to measure the influence of age on cutaneous wound healing
  • organism-icon Homo sapiens
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

The aim of this experiment was measure the influence of age on cutaneous wound healing using human subjects. Increaded age has been associated with delayed wound healing in mouse models and in humans. Gene expression was compared between excisional biopsy wounds from young and old subjects.

Publication Title

Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly.

Sample Metadata Fields

Sex, Age, Specimen part

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accession-icon E-MEXP-265
Transcription profiling of Arabidopsis stem, leaf and hypocotyl tissue undergoing varying amounts of secondary cell wall synthesis
  • organism-icon Arabidopsis thaliana
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

The aim of this experiment was to understand secondary cell wall formation as it is a major constituent of wood and plant fibres. To identify potential novel genes involved in this process, data has been generated from Arabidopsis stem, leaf and hypocotyl tissue undergoing varying amounts of secondary cell wall synthesis.

Publication Title

Identification of novel genes in Arabidopsis involved in secondary cell wall formation using expression profiling and reverse genetics.

Sample Metadata Fields

Age, Specimen part

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accession-icon E-MEXP-515
Transcription profiling of diabetic neuropathy in dorsal root ganglia from streptozotocin-diabetic male wistar rats over the first 8 weeks of diabetes
  • organism-icon Rattus norvegicus
  • sample-icon 7 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Genome 230 2.0 Array (rat2302), UNKNOWN

Description

A study of diabetic neuropathy in dorsal root ganglia from streptozotocin-diabetic male wistar rats over the first 8 weeks of diabetes

Publication Title

Identification of changes in gene expression in dorsal root ganglia in diabetic neuropathy: correlation with functional deficits.

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Disease stage, Time

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accession-icon E-MEXP-268
Transcription profiling of asymptomatic and symptomatic atherosclerotic plaques from the same patient
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U95 Version 2 Array (hgu95av2)

Description

We compared gene expression profiles between asymptomatic and symptomatic atherosclerotic plaques from the same patient. This was accomplished by analyzing carotid plaques from four patients with bilateral high-grade carotid artery stenoses one being symptomatic (TIA or stroke) and the other asymptomatic.

Publication Title

Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques.

Sample Metadata Fields

Sex, Age, Specimen part, Disease, Disease stage, Subject, Time

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accession-icon SRP103454
Homo sapiens isolate:HEK293T Epigenomics
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

CBX7-RIP-Seq data for HEK293T cells

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Cell line

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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