Filters
Technology
Platform
SRP179778
Drosophila melanogaster
45 Downloadable Samples
Illumina HiSeq 2500
Description
Test effects of mtDNA variation on nuclear transcript expression using various mtDNA haplotypes on isogenic nuclear backgrounds
Publication Title
No associated publication
Sample Metadata Fields
Sex, Age, Specimen part, Cell line
View Samples- Drosophila melanogaster
- 23 Downloadable Samples
- Illumina HiSeq 2000
Description
Mitonuclear transcriptomics
Publication Title
No associated publication
Sample Metadata Fields
Sex, Age, Specimen part, Cell line, Treatment
View Samples- Drosophila melanogaster
- 6 Downloadable Samples
- Illumina HiSeq 2000
Description
Early embryo RNA-seq sequencing
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part
View Samples- Drosophila melanogaster
- 9 Downloadable Samples
- Illumina HiSeq 1500
Description
The goal of this study is to characterize the genes that are specifically expressed in the shaft cells of olfactory sensory organ precursors, and regulate nanopore formation on cuticular sheath. To this end, pupal antennae of a wild type strain and two mutant strains (amos and neur>Nb) of Drosophila were subjected to RNA-seq analysis.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Macaca mulatta, Mus caroli, Mus musculus, Pan troglodytes, Pongo pygmaeus, Homo sapiens, Mus spretus
- 13 Downloadable Samples
Affymetrix Murine Genome U74A Version 2 Array (mgu74av2), Affymetrix Human Genome U95 Version 2 Array (hgu95av2)
Description
Microarray technologies allow the identification of large numbers of expression differences within and between species. Although environmental and physiological stimuli are clearly responsible for changes in the expression levels of many genes, it is not known whether the majority of changes of gene expression fixed during evolution between species and between various tissues within a species are caused by Darwinian selection or by stochastic processes. We find the following: (1) expression differences between species accumulate approximately linearly with time; (2) gene expression variation among individuals within a species correlates positively with expression divergence between species; (3) rates of expression divergence between species do not differ significantly between intact genes and expressed pseudogenes; (4) expression differences between brain regions within a species have accumulated approximately linearly with time since these regions emerged during evolution. These results suggest that the majority of expression differences observed between species are selectively neutral or nearly neutral and likely to be of little or no functional significance. Therefore, the identification of gene expression differences between species fixed by selection should be based on null hypotheses assuming functional neutrality. Furthermore, it may be possible to apply a molecular clock based on expression differences to infer the evolutionary history of tissues.
Publication Title
A neutral model of transcriptome evolution.
Sample Metadata Fields
Sex, Age, Specimen part, Disease, Disease stage
View Samples- Oryza sativa
- 18 Downloadable Samples
- Affymetrix Rice Genome Array (rice)
Description
The aim of this study was to analyze potential brown planthopper (BPH) resistant genes in Rathu Heenati (RHT) by Affymetrix whole rice genome array,BPH susceptible and resistant rice varieties of TN1Taichung Native 1as control. All the resistant related genes derived from RHT will be analyzed according to the SSR markers interval flanked on the chromosome 3, 4, 6 and 10. It will be benefit to the gene clone and marker assistant breeding for Bph3 gene in the near future.
Publication Title
Microarray analysis of broad-spectrum resistance derived from an indica cultivar Rathu Heenati.
Sample Metadata Fields
Specimen part, Time
View Samples- Oryza sativa
- 6 Downloadable Samples
- Affymetrix Rice Genome Array (rice)
Description
Drought and salinity are two main abiotic-stresses negatively affecting crop growth and productivity worldwide with largely decreasing crop yields. The understanding of plant responses to stresses in physiology, genetics, and molecular biology will be greatly helpful to improve the tolerance of crops to abiotic-stresses through genetic engineering.To identify the genetic loci that control drought and salt tolerance in rice, we performed a large-scale screen for the mutants with altered drought and salt tolerance. A drought and salt tolerance (dst) mutant line was isolated.In this series, we compare the transcriptome of wild-type plant Zhonghua11 and dst mutants under the normal growth conditions.
Publication Title
A previously unknown zinc finger protein, DST, regulates drought and salt tolerance in rice via stomatal aperture control.
Sample Metadata Fields
Age
View Samples- Arabidopsis thaliana
- 28 Downloadable Samples
- Illumina HiSeq 2000
Description
Arabidopsis thaliana is a main model species for plant science, especially for such branches as molecular biology, genetics and genomics. We present here first genome-wide analysis of expression profiles across different organs and developmental stages using high-throughput transcriptome sequencing (RNA-seq). To determine whether the developmental map represented the majority of the expressed genes, we analyzed gene expression under various abiotic stress conditions.
Publication Title
No associated publication
Sample Metadata Fields
Age, Specimen part, Treatment
View Samples- Pan troglodytes, Homo sapiens
- 15 Downloadable Samples
- Affymetrix Human Genome U95B Array (hgu95b), Affymetrix Human Genome U95D Array (hgu95d), Affymetrix Human Genome U95 Version 2 Array (hgu95av2), Affymetrix Human Genome U95C Array (hgu95c), Affymetrix Human Genome U95E Array (hgu95e)
Description
Gene expression profiling in brain of three adult humans and three adult chimpanzees
Publication Title
DNA sequence and comparative analysis of chimpanzee chromosome 22.
Sample Metadata Fields
Sex, Age, Specimen part, Disease, Disease stage
View Samples- Arabidopsis thaliana
- 26 Downloadable Samples
- Illumina HiSeq 2000
Description
Floral transition is a critical event in the life cycle of a flowering plant as it determines its reproductive success. Despite extensive studies of specific genes that regulate this process, the global changes in transcript expression profiles at the point when a vegetative meristem transitions into an inflorescence have not been described. In this study we analyzed gene expression during Arabidopsis thaliana meristem development from day 7 to 16 after germination in one-day increments. The dynamics of the expression of the main flowering regulators were consistent with previous reports: notably, the expression of FLOWERING LOCUS C (FLC) decreased over the course of the time series while expression of LEAFY (LFY) increased. This analysis revealed a developmental time point between 10 and 12 days after germination where FLC expression had decreased but LFY expression had not yet increased, which was characterized by a peak in the number of differentially expressed genes. GO enrichment analysis of these genes identified an overrepresentation of genes related to the cell cycle, suggesting that during transition to the flowering stage a change in dynamics of cell division takes place. In particular, we hypothesize that a subset of the meristematic cells experiences a forced exit from G0 at day 10. Finally, we observed an acceleration of the cell cycle at day 11, which may be linked to meristem reorganization preceding activation of LFY.
Publication Title
No associated publication
Sample Metadata Fields
Age, Specimen part
View Samples