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accession-icon SRP053216
Danio rerio Transcriptome or Gene expression
  • organism-icon Danio rerio
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2000

Description

Groups of adult zebrafish (9 male and 9 female) were exposed for 7 days to 50 ng/L (168.7 pmol/L) of 17a-ethinylestradiol (EE2). Transcriptome response of EE2 in zebrafish liver were analysed.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP089876
Danio rerio Phenotype or Genotype
  • organism-icon Danio rerio
  • sample-icon 3 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2000

Description

Based on the differential comparison of transcriptomes of Homo-, hetero-zygote (Het) and wild type (Wt), in vivo protein-trap mutagenesis system, we have produced series of expression codex of the zebrafish. Here , we reported the transcriptomic characteristic of a line with stable deficits found in homozygote (Homo) expressing the strongest signal of red fluorescent protein (mRFP) in the central neural system and vascular system.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP136989
Environmental toxins and colon carcinogenesis.
  • organism-icon Homo sapiens
  • sample-icon 16 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

RNA was isolated from colorectal cancer (HCT116) and normal colon cells (HCoEpic) treated with toxic agents (bisphenol A (BPA), hexabromocyclododecane (HBCD), 4-tert-octylphenol (OP)) or Vehicle (DMSO) and then preformed NGS using Illumina protocol.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Disease, Cell line, Treatment

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accession-icon SRP068275
HepG2 (human liver cancer cells) transcriptome with NiO nanoparticles exposure
  • organism-icon Homo sapiens
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIonTorrentProton

Description

The study aims to analysis transcriptome profiles of NiO nanoparticles (NiO NPs) on HepG2 cells. The 100, 25 and 5 ug/ml concentrations of NiO NPs were used to dose the HepG2 cells, respectively

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP044035
Drosophila melanogaster Transcriptome or Gene expression
  • organism-icon Drosophila melanogaster
  • sample-icon 3 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

Deep Sequencing Reveals the Transcriptomic Response to UVA Radiation in the Heads of Drosophila melanogaster (Diptera: Drosophilidae)

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Cell line, Treatment

View Samples
accession-icon GSE16420
Expression profiling and functional analysis of poplar WRKY23 reveals a regulatory role in defense
  • organism-icon Populus tremula x populus alba
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Poplar Genome Array (poplar)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Expression profiling and functional analysis of Populus WRKY23 reveals a regulatory role in defense.

Sample Metadata Fields

Specimen part

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accession-icon GSE16417
Expression profiling and functional analysis of poplar WRKY23 reveals a regulatory role in defense: WRKY23-overexpressor
  • organism-icon Populus tremula x populus alba
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Poplar Genome Array (poplar)

Description

To investigate the function of poplar WRKY23, we generated PtWRKY23-overexpressing and -underexpressing (RNAi) plants. Transgenic plants were inoculated with Melampsora rust or mock-inoculated for assessment of rust-resistance and for gene expression profiling using the poplar Affymetrix GeneChip to study the consequences of PtWRKY23 overexpression and underexpression. Transcriptome analysis of PtWRKY23 overexpressors revealed a significant overlap with the Melampsora-infection response. Transcriptome analysis also indicated that PtWRKY23 affects redox homeostasis and cell wall-related metabolism.

Publication Title

Expression profiling and functional analysis of Populus WRKY23 reveals a regulatory role in defense.

Sample Metadata Fields

Specimen part

View Samples
accession-icon GSE16419
Expression profiling and functional analysis of poplar WRKY23 reveals a regulatory role in defense: WRKY23-RNAi
  • organism-icon Populus tremula x populus alba
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Poplar Genome Array (poplar)

Description

To investigate the function of poplar WRKY23, we generated PtWRKY23-overexpressing and -underexpressing (RNAi) plants. Transgenic plants were inoculated with Melampsora rust or mock-inoculated for assessment of rust-resistance and for gene expression profiling using the poplar Affymetrix GeneChip to study the consequences of PtWRKY23 overexpression and underexpression. Transcriptome analysis of PtWRKY23 overexpressors revealed a significant overlap with the Melampsora-infection response. Transcriptome analysis also indicated that PtWRKY23 affects redox homeostasis and cell wall-related metabolism.

Publication Title

Expression profiling and functional analysis of Populus WRKY23 reveals a regulatory role in defense.

Sample Metadata Fields

Specimen part

View Samples
accession-icon SRP136856
Transcriptomic profiles of zebrafish liver exposed to phenanthrene
  • organism-icon Danio rerio
  • sample-icon 15 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq4000

Description

The present study aims to examine the toxicological effects of phenanthrene in the molecular mechanism in zebrafish. We performed RNA-Seq analysis on zebrafish liver responding to phenanthrene exposure. Genes involved in phenanthrene exposure to zebrafish liver were identified from the transcriptional data. This study provides the completed evaluation of toxic effect of phenanthrene exposure to zebrafish by transcriptional approaches. Our findings could present foundation for further study on molecular mechanism responsible for zebrafish's responses to phenanthrene exposure.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP002572
Drosophila transcriptome
  • organism-icon Drosophila melanogaster
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer

Description

Illumina/Solexa sequencing of CG3985 mutant and wildtype testes transcriptome (0-1 day males)

Publication Title

A young Drosophila duplicate gene plays essential roles in spermatogenesis by regulating several Y-linked male fertility genes.

Sample Metadata Fields

No sample metadata fields

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...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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