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accession-icon GSE61121
White adipose tissue and brain microarray from eIF6 heteroxygotes and wild-type 5 weeks-old mice
  • organism-icon Mus musculus
  • sample-icon 11 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

White adipose tissue is primary involved in the response to insulin after feeding, while brain is not directly sensitive to insulin levels.

Publication Title

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription.

Sample Metadata Fields

Specimen part

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accession-icon GSE61053
Liver microarray from eIF6 heterozygotes or wild-type 3 weeks-old mice
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

Liver is primary involved in the response to insulin after feeding. Hepatocytes activates a tightly controlled genetic programme where specific sets of genes are modulates in response to insulin, for activation of the anabolic pathways.

Publication Title

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription.

Sample Metadata Fields

Specimen part

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accession-icon GSE103523
Gene expression analysis of OX40+ Tregs from human liver tissues
  • organism-icon Homo sapiens
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip

Description

Analysis of the gene signature of OX40+ Tregs, in comparison to OX40- Tregs and Tconvs, freshly isolated from liver cirrhosis and tumor of chronic HCV patients.

Publication Title

Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth.

Sample Metadata Fields

Specimen part

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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