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accession-icon SRP033225
Bos taurus Genome sequencing
  • organism-icon Bos taurus
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

Examination of whole genome gene expression profiles from the placentas of cloned (somatic cell nuclear transfer, SCNT) and normally produced (control) calves using RNA-seq.The differentially expressed genes were analyzed between SCNT and control placentas.

Publication Title

No associated publication

Sample Metadata Fields

Sex

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accession-icon SRP185927
RNA-seq of APMAP knockdown PC-3 cells
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

This study goal is to obtain the different expression genes induced by APMAP knockdown.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon SRP157946
RNA-seq of cholesterol treated PC-3 cells
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

This study goal is to obtain the different expression genes induced by cholesterol.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Disease, Cell line

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accession-icon GSE31106
Expression data for the different phases of ulcerative colitis-associated carcinogenesis in a mouse model
  • organism-icon Mus musculus
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Nonresolving inflammation is correlated to carcinogenesis. Ulcerative colitis-associated colorectal cancer (UC-CRC), one of the typical carcinoma generated by inflammation that cannot be resolved properly, has been widely believed to involve a multistep process contains inflammation-dysplasia-cancer sequence. The exact molecular mechanisms underlying the step-wise development of UC-CRC is still not fully understood. Detecting the changes in gene expression profiles may help to reveal why and how does the prolonged inflammatory response lead to carcinogenesis, and to characterize potential diagnostic/prognostic markers or additional therapeutic targets for UC-CRC. There for, we performed temporal genome expression profiling analysis using the Affymetrix genome wide microarray system to identify broad scale changes in gene expression associated with the development of colitis-associated cancer, based on an AOM/DSS induced mouse model of UC-CRC.

Publication Title

Dynamic activation of the key pathways: linking colitis to colorectal cancer in a mouse model.

Sample Metadata Fields

Disease, Disease stage

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accession-icon GSE53735
Expression data for murine colon carcinoma cell line CT26.WT stimulated with S100a8 or S100a9 recombinant protein
  • organism-icon Mus musculus
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Damage-associated molecular pattern (DAMP) molecules S100A8 and S100A9 with well-known functions in inflammation, tumor growth and metastasis. It has been found to have promote tumor cell proliferation activity at low concentration . However, the mechanism underlying this remains unclear. In the current study, we performed genome expression profiling analysis using the Affymetrix genome wide microarray system to identify broad scale changes in gene expression associated with S100a8 or S100a9 recombinant protein stimulation in murine colon carcinoma cell line CT26.WT.

Publication Title

Inflammation-induced S100A8 activates Id3 and promotes colorectal tumorigenesis.

Sample Metadata Fields

Cell line

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accession-icon SRP047266
Homo sapiens Transcriptome or Gene expression
  • organism-icon Homo sapiens
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIlluminaHiSeq2000

Description

To investigated a detailed analysis of the transcriptional response between epithelial Caco-2 cells with different Bifidobacterium animals subsp. lactis KLDS 2.0603 cells ( Control and cells treated by digestive tract fluids simulated ).

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP111420
Bacterial co-culture
  • organism-icon Pseudomonas aeruginosa
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Laboratorial research

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Cell line

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accession-icon SRP081186
human gene Transcriptome
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

human gene Transcriptome analysis

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part

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accession-icon E-MTAB-2419
Comparative Transcriptome Analysis between SOL and EDL Muscle in Yorkshire pigs using Affymetrix microarray
  • organism-icon Sus scrofa
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

Description

Skeletal muscle is heterogeneous in nature and distinguished as red muscle and white muscle because of their myofiber composition. Soleus (SOL) is a typical red muscle and extensor digitorum longus (EDL) is a typical white muscle. In this study, we compared the transcriptome difference of soleus and extensor digitorum longus from three 10-week-old Yorkshire boars with porcine Affymetrix microarray.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Subject

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accession-icon SRP092744
Genes and polymorphism identification associated to hernias in swine
  • organism-icon Sus scrofa
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Transcriptome of connective tissue of swine affected and non-affected with scrotal hernia

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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