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accession-icon SRP019983
Small RNA transcriptome in murine liver during Schistosoma japonicum infection
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer

Description

Small RNA transcriptome in murine liver during Schistosoma japonicum infection.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Disease, Disease stage

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accession-icon SRP060202
low and high dose TLR4 stimulation in bone-marrow derived mouse macrophages
  • organism-icon Mus musculus
  • sample-icon 10 Downloadable Samples
  • Technology Badge IconNextSeq 500

Description

The goal of this study was to compare gene expression in mouse bone marrow-derived macrophages stimulated with high or low doses of the TLR4 ligand Kdo2-Lipid A.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP167225
Characterization of Transcriptomic Profile in Early Zebrafish PGCs by Single Cell Sequencing
  • organism-icon Danio rerio
  • sample-icon 9 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Single cell RNA-seq was applied for studying the transcriptomic profile in early zebrafish PGCs(primordial germ cells) by choosing three time points during zebrafish embryonic development. The three time points were 6hpf(hours post fertilization, also called shield stage), 11hpf(also called 3-somite stage) and 24hpf(also called prim-5 stage).

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon SRP076058
Zea mays Raw sequence reads
  • organism-icon Zea mays
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

This study presented the differentially expressed genes post maize infected by Rhizoctonia solani.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon SRP044629
Mus musculus strain:a C57BL/6;129/SvEv mixed background Transcriptome or Gene expression
  • organism-icon Mus musculus
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer II

Description

To investigate the molecular mechanism which caused the defect of aberrant somatic cell differentiation in Wt1-deficient gonads, the differentially expressed genes between control and Wt1-deficient gonads at E11.5 was analyzed by RNA Seq analysis.After tamoxifen injection at E9.5, total RNA was prepared from control and Wt1-deficient gonads at E11.5 using RNeasy Minikit (Ambion, Austin, TX). Gonads of the same genotype (about 12 pairs each) were pooled together. For RNA-Seq, the main reagents and instruments used for RNA library construction and deep sequencing were the Illumina Gene Expression Sample Prep Kit, Solexa Sequencing Chip (flowcell), Illumina Cluster Station and Illumina HiSeq 2000 System. Sequence tags were prepared using the Illumina Digital Gene Expression Tag Profiling Kit, according to the manufacturer's protocol. Raw data was filtered to remove adaptor tags, low quality tags, and tags with a single copy number. Paired-end reads were mapped to the mouse genome (mm9) with TopHat and further analyzed by Cufflinks-Cuffdiff (Trapnell et al., 2009; Trapnell et al., 2010) pipelines to identify differentially expressed transcripts (DETs) between control and Wt1-deficient gonads.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE99055
Global gene expression in Abp57-overexpressing transgenic rice
  • organism-icon Oryza sativa indica group
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Rice (Chinese Build) Gene 1.0 ST Array (rcngene10st)

Description

An auxin-binding protein (Abp57) was previously isolated from rice and known to activate plasma membrane proton ATPase. The Abp57 function was characterised by overexpression in the rice and Arabidopsis. The transgene expression was driven by constitutive promoter, CaMV35S. Results from physiological experiments showed that the transgenic lines were tolerant to drought and salinity stress.

Publication Title

Microarray dataset of transgenic rice overexpressing <i>Abp57</i>.

Sample Metadata Fields

Age, Specimen part

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accession-icon SRP173014
Fzr-mediated endoreplication in Drosophila
  • organism-icon Drosophila melanogaster
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

A novel transcriptional cascade involved in Fzr-mediated endoreplication

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon SRP093478
Mulberry MnMAPK6, a group C mitogen-activated protein kinase gene, endowed novel response to various abiotic stresses in transgenic Arabidopsis
  • organism-icon Arabidopsis thaliana
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

There is limited knowledge on the biological function of group C MAPK. To reveal the function of MnMAPK6, a group C MAPK, in the transgenic Arabidopsis, a transcriptome analysis was performed by Illumina sequencing for the assessment of gene expression changes between WT and MnMPK6-overexpressed Arabidopsis.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Treatment

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accession-icon E-ATMX-13
Transcription profiling by array of Arabidopsis cell suspensions after treatment with methyl jasmonate
  • organism-icon Arabidopsis thaliana
  • sample-icon 14 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

The transcriptional response of Arabidopsis thaliana cell suspensions following treatment with the stress hormone methyl jasmonate (MeJA) was monitored over time 16 hours after subcultivation. Three time points were included: 30 minutes, 2 hours and 6 hours after elicitation with 50µm MeJA or DMSO as a control.

Publication Title

Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cells.

Sample Metadata Fields

Compound, Time

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accession-icon SRP065059
Zea mays cultivar:Shandan 609 Raw sequence reads
  • organism-icon Zea mays
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

This study provide a dynamic atlas of endosperm development from Shaanxi within China

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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