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accession-icon SRP035483
Bos taurus strain:Hanwoo Transcriptome or Gene expression
  • organism-icon Bos taurus
  • sample-icon 1 Downloadable Sample
  • Technology Badge IconIllumina HiSeq 2000

Description

Although it is well known that the function of MyoG cannot be compensated for other MRFs, the molecular mechanism by which MyoG controls muscle cell differentiation is still unclear. Therefore, in this study, RNA-Seq technology was applied to profile changes in gene expression in response to MyoG knock-down (MyoGkd) in primary bovine muscle satellite cells (MSCs). This study is the first RNA-Seq based gene expression analysis of MyoGkd undertaken in primary bovine MSCs.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Disease

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accession-icon SRP020868
Glycine max Transcriptome or Gene expression
  • organism-icon Glycine max
  • sample-icon 9 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

To provide novel insights into the molecular basis of floral initiation, RNASeq was used to characterize the soybean transcriptome of leaf and micro-dissected shoot apical meristem at different time points after short-day treatment.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP039327
Mus musculus Thymus Transcriptome from embryo to adult
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

Total RNA of thymus from mouse different development stages were isolated and deeply sequenced by SAPAS to investigated the global gene regualtion events during thymus genesis and maturation.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon SRP039399
Homo sapiens Transcriptome or Gene expression
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIlluminaGenomeAnalyzerIIx

Description

Rectal cancer stage II carcinoma and adjacent normal tissue transcriptome

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

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accession-icon E-ATMX-24
Transcription profiling of Arabidopsis Umkirch-1/Umkirch-3 hybrid plants grown at 23C and 16C in short day conditions
  • organism-icon Arabidopsis thaliana
  • sample-icon 18 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Umkirch-1/Umkirch-3 hybrid plants and their parents were grown at 23SD and then shifted to 16SD for five days. 10 plants were pooled in each of three sample replicates.

Publication Title

Autoimmune response as a mechanism for a Dobzhansky-Muller-type incompatibility syndrome in plants.

Sample Metadata Fields

Specimen part

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accession-icon SRP189374
Pseudomonas aeruginosa PA14 response to surface attachment on a plastic petridish
  • organism-icon Pseudomonas aeruginosa
  • sample-icon 18 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

RNASeq time course (1,2,3 hrs) of Pseudomonas aeruginosa (UCBPP-PA14) on plastic (polystyrene) petri dish

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Disease, Cell line

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accession-icon SRP165680
Evaluation of cryopreserved primary nasal and bronchial epithelial cells for rhinovirus infection in- vitro studies
  • organism-icon Homo sapiens
  • sample-icon 12 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

There is increasing interest in using primary nasal epithelial cells (PNECs) instead of primary bronchial epithelial cells (PBECs) in order to study epithelial responses in rhinitis and asthma. This study aimed to establish a robust cell culture model appropriate for studying rhinovirus infection and the consequent epithelial responses in asthma and rhinitis. First, a comprehensive comparison of fresh and cryopreserved primary nasal epithelial cells from three donors before and after RV infection was conducted, using high throughput RNA sequencing and transcriptomics.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part

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accession-icon SRP130653
Mutational signatures reveal the role of RAD52 in p53-independent p21 driven genomic instability
  • organism-icon Homo sapiens
  • sample-icon 12 Downloadable Samples
  • Technology Badge IconNextSeq 500

Description

Genomic instability promotes evolution and heterogeneity of tumors. Unraveling its mechanistic basis is essential to design appropriate therapeutic strategies. In a recent study we reported an unexpected oncogenic property of p21WAF1/Cip1 showing that its chronic expression, in a p53-deficient environment, causes genomic instability by deregulating the replication licensing machinery.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

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accession-icon ERP002588
RNA-seq data for cell lines in the haematopoietic lineages, hematological malignancy
  • organism-icon Homo sapiens
  • sample-icon 7 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2000

Description

RNA-seq data for cell lines in the haematopoietic lineages, hematological malignancy

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon E-MEXP-445
Transcription profiling by array of human primary monocytes grown in hypoxia
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Experiment with 6 hybridizations, using 30 samples of species [Homo sapiens], using 6 arrays of array design [Affymetrix GeneChip Human Genome HG-U133A [HG-U133A]], producing 6 raw data files and 6 transformed and/or normalized data files.

Publication Title

Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene.

Sample Metadata Fields

Specimen part, Disease

View Samples
...

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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