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accession-icon SRP082943
Zea mays Transcriptome on PPDK
  • organism-icon Zea mays
  • sample-icon 72 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

To reveal the dynamic expression of genes involved in PPDK regulation, different leaf sections of PPDK mutant, wild type and its heterozygous, which were grown under high and low light, were subjected to RNA-seq sequencing.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon SRP096846
Histone Acetyltransferase GCN5 Contributes to Stem Cuticular Wax Biosynthesis by Acetylating ECERIFERUM 3 (CER3) in Arabidopsis thaliana
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

Cuticular wax is a major composition of plant surface cuticle, which exerts crucial functions in optimizing plant growth. Histone acetylation regulates gene expression of diverse biological processes, but little is known about its role in cuticular wax synthesis. Here we observed that mutation of Arabidopsis histone acetyltransferase GCN5 gene impaired stem cuticular wax accumulation. Furthermore, three target genes of GCN5 (CER3, CER26 and CER1-L1) were identified by RNA-Seq and ChIP assays. Consistently, H3K9/14 acetylation levels in promoter regions of CER3, CER26 and CER1-L1 were significantly decreased in gcn5 as compared to wild type. Notably, overexpression of CER3 in the gcn5 mutant restored the stem cuticular wax accumulation. Collectively, these data demonstrate that Arabidopsis GCN5 is involved in stem cuticular wax accumulation by modulating CER3 expression via H3K9/14 acetylation, which present evidence that histone acetylation plays an important role in cuticular wax biosynthesis

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

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accession-icon GSE31434
Expression data from HeLa cells transfected with SLC44A5
  • organism-icon Homo sapiens
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

We identified SLC44A5 as a gene associated with birth weight in cattle based on genome wide association studies.

Publication Title

The molecular effects of a polymorphism in the 5'UTR of solute carrier family 44, member 5 that is associated with birth weight in Holsteins.

Sample Metadata Fields

Cell line

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accession-icon GSE5231
IGF1R Mediates Mammalian Immune Function in Response to FEZL
  • organism-icon Homo sapiens
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP132125
ZmGRP1 CRISPR/Cas9 RNA sequencing
  • organism-icon Zea mays
  • sample-icon 7 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

To study the splicing factor role of ZmGRP1

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Disease, Disease stage, Cell line, Treatment

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accession-icon GSE5225
Expression data from OCUBM cells trasfected with IGF1R
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

To investigate genes that might influence resistance to infection through IGF1R, we screened human breast cancer-derived OCUB-M cells transfected with expression vector encoding IGF1R using microarray analysis.

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP077851
Zea mays Transcriptome or Gene expression
  • organism-icon Zea mays
  • sample-icon 5 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

The Mechanisms of Maize Resistance to Fusarium verticillioides by comprehensive analysis of RNA-seq Data

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part, Disease, Disease stage, Treatment

View Samples
accession-icon GSE5224
Expression data from OCUBM cells trasfected with 12G FEZL
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

To identify genes that influence resistance to mastitis, we scanned

Publication Title

Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP014902
Sus scrofa strain:Duroc and wild boar Transcriptome or Gene expression
  • organism-icon Sus scrofa
  • sample-icon 3 Downloadable Samples
  • Technology Badge IconIllumina Genome Analyzer IIx

Description

Pig RNA-seq.

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP095378
Arabidopsis thaliana Raw sequence reads
  • organism-icon Arabidopsis thaliana
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

Transcriptomic analysis of BnLATE-regulated pathways to investigate the genome-wide effects of BnLATE overexpression on transcription

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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